GPU × Model Compatibility

Can a NVIDIA GeForce RTX 4060 Ti (16GB) run Qwen 2.5 (72B)?

NVIDIA GeForce RTX 4060 Ti (16GB) has 16GB VRAM. Here's exactly whichprecision (FP16, FP8, GGUF)of Qwen 2.5 (72B) fits and how smoothly it runs.

Too much for this GPU

The NVIDIA GeForce RTX 4060 Ti (16GB) (16GB) doesn't have enough VRAM for Qwen 2.5 (72B) even at its smallest size (43.2GB needed). Rent a cloud GPU or step up to a bigger card.

43.2GB
smallest fit on this GPU

Run it in the cloud instead

A 24GB RTX 4090 instance runs Qwen 2.5 (72B) at full quality, starting at pennies/hour.

Disclosure: Cloud provider links are referrals at no additional cost to you.

Qwen 2.5 (72B) variants on the NVIDIA GeForce RTX 4060 Ti (16GB)

VariantPrecisionSizeTotal VRAM neededHeadroomFits?
Q4_K_M (4-bit Recommended)RECq4_k_m43.2GB43.2GB-27.2GB✗ OOM
Q8_0 (8-bit GGUF)q8_081.2GB81.2GB-65.2GB✗ OOM
FP16 (Uncompressed)fp16152.2GB152.2GB-136.2GB✗ OOM

"Total VRAM needed" = variant size + 0.0GB estimated text-encoder/VAE overhead. Headroom = GPU VRAM (16GB) − total needed. Green ≥ 1.5GB headroom; Red ≤ −2GB (will OOM).

NVIDIA GeForce RTX 4060 Ti (16GB) at a glance

VRAM
16GB
Est. price
$450
Best for
145.4GB Qwen 2.5 (72B) and lighter

Other models on the NVIDIA GeForce RTX 4060 Ti (16GB)

Other GPUs for Qwen 2.5 (72B)